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Infergen is the brand name for consensus interferon. It is a totally artificial alfa interferon, and is chemically different from the interferon in PegIntron and Pegasys. Infergen is not available yet as a pegylated interferon, so it must be taken several times each week, preferably daily. At AASLD 2007 the results of the Direct trial were presented. This was a medium sized study where peginterferon nonresponders were given Infergen and ribavirin daily. Many of the patients had stage 3 or 4 fibrosis. About ten percent were sustained viral responders. We offer Infergen 15mcg daily plus ribavirin to nonresponders. |