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I am excited about HCV protease inhibitors which are orally active drugs with great strength. Telaprevir from Vertex Pharmaceuticals has been named Incivek, and it drops the viral level by about 99.9% in less than a week. Press releases have details
concerning the studies and can be read at
The summary information was released by
Vertex on 10-30-10. Read it
telaprevir for every 8 hour dosing.
A
The FDA approved telaprevir, pegylated interferon and ribavirin in combination for HCV. For FDA briefing documents, click
of medicine, For the full FDA approved package insert
click
The majority of patients will choose to be treated with triple therapy using telaprevir, Pegasys and ribavirin. If they fail this, they might
be able to enroll in a clinical trial with a new agent.
of protease inhibitor, polymerase inhibitor, Pegasys and ribavirin will push the success rate higher. If you are interested in participating in a clinical trial to
test new drugs go to
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