DOCTOR HOME since
Welcome to patients with chronic viral hepatitis
B or C and to their loved ones. Sofosbuvir is a
polymerase inhibitor that is combined
with ribavirin for treatment of patients with genotype 2
and genotype 3 patients. Pegasys or
PegIntron is added for patients with genotype 1, 4, 5 and 6.
Sofosbuvir does not have the
drug interaction problems and rash found with telaprevir, a protease
inhibitor. Treatment is 12 weeks in
length. Genotype 3 patients have a higher success rate with 16
or 24 weeks. If you are cured, your viral level falls to undetectable
during treatment and stays
undetectable the rest of your life, after
you stop the medications. If
detectable in your blood, you were not cured. If your HCV-RNA is undetectable 6 months after
your last injection of interferon, you have a 99%
chance of permanent cure. Liver damage stops
and liver healing starts. This
improves survival and often restores health. You can read the PDF file
poster from AASLD, that demonstrates improved survival
when HCV is cured.
PDF file of AASLD poster
I add information to this web site
as often as I can, and I want to make it a resource for patients whom
are often incorrectly told that they cannot be helped. The opinions expressed here
are entirely my
own, and are based on my experience in treating more
than 4,000 patients with hepatitis C.
I am especially excited about the new
oral medicines for patients with hepatitis C. I am a board
certified in internal medicine and gastroenterology.
In addition, I completed 2 years of residency
in pathology at Duke University Medical Center. I have been
a physician for 36 years. I spend about
95% of my time treating patients with chronic viral hepatitis
C. I enjoy helping as many patients as
possible cure this infection.